Gamma-butyrolactone is an excipient for the painting of textile fibres and polymerisation initiator and is suitable for many applications. Improving sexual performance and pleasure. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Mediterranean, Low-Fat Diets Are Best for Heart Problems, Least Amount of Exercise You Need to Stay Healthy, Nerve 'Pulse' Therapy May Help Ease Sciatica, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, The Role Gut Bacteria Plays on the Overall Body. -Hydroxy--butyrolactone may be employed as starting reagent in the . % C p,gas: Constant pressure heat capacity of gas: C p,liquid: Constant pressure heat capacity of liquid: P c: Critical pressure: S liquid Entropy of liquid at standard conditions GBL is changed in the body to gamma-hydroxybutyrate (GHB). This substance is used Neurosci Biobehav Rev 1989;13:187-98. outdoor use. 96-48-0, Mol. Possession is not illegal, but may be punished according to the Medicines Act, when intended to be sold for human consumption or synthesis of GHB. GBL EU can be found in cheese flavorings but typically results in a content of 0.0002% GBL in the final foodstuff. GAMMA BUTYROLACTONE (GBL) - Uses, Side Effects, and More - WebMD Information on precautionary measures and the safe use is submitted by the registrant of a substance and the registrant is solely responsible for its accuracy and completeness. [5][6] This finding indicates that GBL is a naturally occurring component in some wines and may be present in similar products. Surgery: GBL can affect the central nervous system (CNS). causes serious eye damage and Most polymers will melt when exposed to it. Gamma-Butyrolactone - an overview | ScienceDirect Topics Lyondell reportedly stopped commercial sales of this product due to increasingly tight regulations and liabilities but still makes it for internal and downstream production use. The first reported UK fatality related to gamma-butyrolactone (GBL) ingestion. Our well-developed distribution network ensures that all products you get arrive on time, are dispatched to the most convenient locations for collection, and are delivered on time to your specified address; we are swift and dependable. A license is mandatory for the manufacture, processing, reworking, importing, distribution of GBL.[40]. : 96-48- InfoCards are updated when new information is available. March 2022. It is possible for oral ingestion of GBL to cause nausea and other similar problems, possibly more so than with GHB. Buy GBL Gamma Butyrolactone Online, Its difficult to store because it requires a glass bottle or a certain sort of plastic bottle. Some medications for pain include meperidine (Demerol), hydrocodone, morphine, OxyContin, and many others. Rapidly hydrolyzed by bases and slowly hydrolyzed by acids. Reaction with methylamine gives NMP, and with ammonia gives pyrrolidone. [4], In the laboratory, it may also be obtained via the oxidation of tetrahydrofuran (THF), for example with aqueous sodium bromate. [Letter and responses]. The 'Substance identity' section is calculated from substance identification information from all ECHA databases. Ellinwood EH Jr, Gonzalez AE, Dougherty GG Jr. Gamma-Butyrolactone effects on behavior induced by dopamine agonists (abstract). Although recently passed legislation to enter into force on 1 April 2011 will make it possible to handle narcotics for industrial purposes will enable GBL and 1,4-Butanediol to be classified as controlled substances. /Producer(Sub Systems, Inc.)/CreationDate(D:20211224182411+05'00')/ModDate(D:20211224182411+05'00')/Creator(Sub Systems, Inc.) learn more about gamma butyrolactone. 28 results for "gamma-butyrolactone" Results Price and other details may vary based on product size and color. Sivilotti ML, Burns MJ, Aaron CK, Greenberg MJ. Europe Gamma Butyrolactone Market Report Highlights. gamma butyrolactone bunnings where to buy gamma-butyrolactone buy gbl online australia gbl cleaner bunnings how to extract gbl gbl australia gbl wheel cleaner australia buy gbl online how to extract gbl from wheel cleaner buy gbl cleaner uk best place to buy gbl buy gbl online usa gbl cleaner amazon Kohrs FP, Porter WH, et al. Neurol 1980;30:832-8. [13], It has been used as a solvent in various laboratory experiments, e.g., the preparation of methylammonium lead halide.[14]. stream 2020 Jun;27(3):223-227. Acad Emerg Med 2002;9:730-39.. View abstract. If available, additional information on classification and labelling (C&L) is derived from REACH registration dossiers submitted by industry. However, when consumed in excessive amounts with a high frequency of dosing, physical and psychological dependence can develop. Other release to the environment of this substance is likely to occur from: View abstract. People use it as medicine. I got the 5L, FDA Talk Paper. [22], Due to the fact that those with limited chemistry knowledge can make GBL with easy-to-get precursors, it has become quite popular among young people in French nightclubs.[23][24]. Find out more on how we use cookies. washing & cleaning products, Use of GBL, or the closely related gamma hydroxybutyrate (GHB) and butanediol (BD), has been linked to deaths and cases of serious side effects. The purification takes place with a liquid-gas-phase extraction. [15] GBL is more lipophilic (fat soluble) than GHB, and so is absorbed faster and has higher bioavailability. adhesives and sealants, FDA alert on misuse of consumer products containing GHB, GBL and BD. To bypass GHB restriction laws, home synthesis kits were introduced to transform GBL and/or 1,4-B into GHB. Taking naloxone along with GBL might decrease the effects of naloxone. Arch Intern Med 1999;159:2221-4. inks and toners, Do not take GBL if you are taking sedative medications. 1999. Gamma hydroxybutyrate is not a GABA agonist (abstract). If taken undiluted by mouth, GBL can cause esophageal and gastro-intestinal irritation. Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed. Circular 004/2022: Gamma-Butyrolactone (GBL) and 1,4 - GOV.UK Washington, DC 20009, Designated drugs are ordinarily placed in Schedule 1 to the 2001 Regulations. Do not take GBL if you have been drinking. It may be an option if surgery is too risky due to your age or other health problems or if the tumor cannot safely be reached with surgery. : 96-48- 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Synthesis of substances 1.3 Details of the supplier of the safety data sheet Company : Sigma-Aldrich Inc. 3050 SPRUCE ST In humans GBL acts as a prodrug for -hydroxybutyric acid (GHB), and it is used as a recreational CNS depressant with effects similar to barbiturates. And is available commercially as an industrial solvent and as an ingredient in cleaners, paint removers, and engine degreasers. In recent years, an increase of GBL consumption has been observed due to the prohibition of GHB. Other monikers Therefore we try to create an atmosphere of trust and honesty. It does not represent a new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects described, such as duration of exposure or substance concentration (e.g. However, substance notifications in the InfoCard are aggregated independently of the impurities and additives. Wickr ID :::gblghl2 gamma-Butyrolactone (GBL) in Los Angeles, CA 99.9% GBL Gamma-Butyrolactone GBL , GHB , BDO Alloy wheel cleaner buy gbl online gbl cleaner bunnings - Gbl Wheel Cleaner | Facebook 1 0 obj This substance can be found in complex articles, with no release intended: pure gbl for sale, Gamma-Butyrolactone Liquid (GBL) is a clear liquid solvent containing gamma butyrolactone (geeb). Substances for which classification and labeling data have been submitted to ECHA in a registration under REACH or notified by manufacturers or importers under CLP. VIew abstract. United States, 1841 Columbia Rd NW, Washington, DC 20009, United States. Our Shop does not intend to promote or incite the use of illegal or controlled substances. However, GBL and 1,4-BD were not placed in a schedule. Public (risk management) activities co-ordination table. Its trafficking is limited, and non-licensed selling, buying or any other use is punishable by imprisonment up to 20 years. All Photos (1) -Methylene--butyrolactone. : adhesives and sealants, GHB has biphasic effects, an euphoric effect at low doses (the reason for the term liquid ecstasy), and a sedative effect[25] at higher doses. It is volatile with steam. in case of consumer and professional uses). Increasing mental clarity. RxList does not provide medical advice, diagnosis or treatment. Extreme ?-butyrolactone overdose with severe metabolic acidosis requiring hemodialysis. Buy GAMMA-BUTYROLACTONE (GBL) Online, Identifiers View abstract. Gamma-Butyrolactone Regulatory System of Streptomyces chattanoogensis Links Nutrient Utilization, Metabolism, and Development 20/06/2011. FDA Warns About GBL-Related Products. Anon. Harmonisation is based on the substances physical, toxicological and eco-toxicological hazard assessment. Acidity (pKa) 4.5 Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned. REACH regulationaims to improve the protection of human health and the environment from the risks that can be posed by chemicals. gbl cleaner amazon. Details of the supplier of the safety data sheet !|3i2 daaLg!XuL! ]];g! coating products, SAFETY DATA SHEET - Fisher Sci methyl-2-pyrrolidone. MMWR Morb Mortal Wkly Rep 1999;48:137-40. Food and Drug Administration, Rockville, MD. Alias: Gamma Butyrolactone, y-Butyroladone, 1, 4- Butyrolactone, Blo Cas No. View abstract. ChEMBL CHEMBL95681 The examples provided are generic examples and may not apply to the specific substance you are viewing. methyl-2-pyrrolidone. Alcohol can cause sleepiness and drowsiness. If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9. Thanks! HR 2130. Do not take GBL if you are taking medications for a mental condition. g-Butyrolactone ReagentPlus , = 99 96-48-0 - Sigma-Aldrich These compounds then may go on to form the polymer poly(4-hydroxybutyrate) as well as the dimer 1,6-Dioxecane-2,7-dione. Dealing with GBL Shop means that your order will be shipped. Magnfico! formulation of mixtures and/or re-packaging. Identification of the date-rape drug GHB and its precursor GBL - PubMed Be careful not to confuse gamma butyrolactone (GBL) with gamma hydroxybutyrate (GHB). polymers, In the body, GBL is converted to gamma-hydroxybutyrate (. The 2021 Regulations placed two controlled drugs, Gamma-Butyrolactone (GBL) and 1,4-Butanediol (1,4-BD), which have legitimate uses in industry, under stricter control, meaning that industrial . Dont include personal or financial information like your National Insurance number or credit card details. View abstract. Although it is illegal in the US, GBL has been used as a party and date-rape drug. Ann Emerg Med 1999;33:475-6. For all of your demands, visit our research chemical store, get high purity from us, and save 10% with our coupon code. 1841 Columbia Rd NW, It is possible that a harmonisation is introduced through an amendment to the CLP Regulation. REACH registration dossiers have greater data requirements (such as supporting studies) than do notifications under CLP. 106th Congress of the United States of America. And as a solvent in some wet aluminum electrolytic capacitors. Medications that cause sleepiness and drowsiness are called sedatives. [citation needed]. One of the furans with a carbonyl thereby forming a cyclic lactone. Butyrolactone - NIST J R Soc Med 2009;102(12):546-7. In terms of revenue, electrical application accounted for the highest share of more than 36.0% in 2020 on account of increasing demand for . CAS number 96-48-0 GBL has been found in extracts from samples of unadulterated wines. Buy GAMMA-BUTYROLACTONE LIQUID (GBL) Online, USA is our Main market of Supply for GBL, Customers pleasure is our main goal, and we are here to serve them. 1,4-butanediol to gbl 1,4-butanediol buy 1,4-butanediol price 1,4-butanediol dosage 1,4-butanediol suppliers 1,4-butanediol cleaner Taking ritonavir with GBL might decrease how quickly the body gets rid of GBL. Fatality due to gamma-hydroxybutyric acid (GHB) and heroin intoxication. Showing 1-30 of 52 results for "gamma-butyrolactone" within Products. Eur J Emerg Med. Australia: GBL is not classified as a drug but as a health-endangering substance. I received my shipment. View abstract. Taking both of these medications plus GBL might decrease how quickly the body gets rid of GBL. Registration, Evaluation, Authorisation and Restriction of Chemicals, Chemical Agents Directive and Carcinogens or Mutagens Directive, C&L Inventory, Registration dossier, Other, Butanoic acid, 4-hydroxy-, .gamma.-lactone, EC Inventory, C&L Inventory, Registration dossier, Pre-Registration process, Other, Substances of very high concern identification, Recommendation for the Authorisation List, Getting started with EU chemicals legislation, Classification of substances and mixtures, Harmonised classification and labelling (CLH). View abstract. Dont worry we wont send you spam or share your email address with anyone. Some medications used to prevent seizures include phenobarbital, primidone (Mysoline), valproic acid (Depakene), gabapentin (Neurontin), carbamazepine (Tegretol), phenytoin (Dilantin), and others. polymers and More information about CAS and the CAS registry can be found here. June 15, 1999. J Toxicol Clin Toxicol 1997;35:581-90. Taking GBL along with sedative medications might cause serious side effects. CAS No. i got the 50L gbl, Ele Vai Pedir Voc Em Namoro Em 30 Dias August 26, 2022, reliable vendor and product arrived at drop off location within 4 days (120L shipped!) Substances Act. [10][11] It is claimed that poly(GBL) is competitive with commercial biomaterial poly(4-hydroxybutyrate), or P4HB. CAS96-48-. Tunnicliff, G. Sites of action of gamma-hydroxybutyrate (GHB)-a neuroactive drug with abuse potential. The EC or list number is the primary substance identifier used by ECHA. In the US, it is illegal to manufacture or sell GBL or the related products GHB and butanediol (BD). We expressly point out that we cannot be held responsible for the future actions of those who purchase products from this site. Phytochem 1996;41:531-6. ogromne zamwienie nadchodzi ode mnie? For a detailed overview on identified uses and environmental releases, please consult the registered substance factsheet. Ann Emerg Med 2011;58(1):83-5. 2001;344:87-94.. View abstract. for thermoplastic manufacture. Nonstrained -Butyrolactone to High-Molecular-Weight Poly( Cash CD. The EC Number is the numerical identifier for substances in the EC Inventory. Save my name, email, and website in this browser for the next time I comment. I fully vouch for these guys any day! The Schedule into which a drug is placed is based on an assessment of its medicinal or therapeutic usefulness, the need for legitimate access as well as its potential for harm when used. WebMD does not provide medical advice, diagnosis or treatment. X`I%&/m{JJt`$@iG#)*eVe]f@{{;N'?\fdlJ!?~|? Wonderful vendor fast shipping easy going! GBL is changed in the body to GHB (gamma hydroxybutyrate). Substances may have impurities and additives that lead to different classifications. [33] This is where the user has become tolerant to the effects of the drug, increasing the dosage and frequency of dosage simply to avoid withdrawal symptoms. thanks, Thank you for posting the 50L arrived New Zealand safely after 5 days (delayed), To byo bardzo szybkie od tego, dziki raz za razem, Das war sehr schnell im Vergleich zu einem chinesischen Lieferanten, I ordered and shipped to two separate locations in TX, Cm n ngi bn ca ti ni vi ti v Trang web ny. van Gerwen M, Scheper H, Touw DJ, van Nieuwkoop C. Life-threatening acute lung injury after gamma butyrolactone ingestion. We specializes in the sale of Gamma-butyrolactone all over the world. Buy Gbl Online from Gbl shops(Gamma-Butyrolactone -butyrolactone ) is a hydroscopic colorless liquid. View abstract. Prog Neurobiol 1997;51:337-61. DrugBank DB04699 N Engl J Med 1998;339:847-8. Buy GAMMA-BUTYROLACTONE LIQUID (GBL) Online is a hygroscopic chemical that is soluble in water and has a slight distinctive odor, GBL is a popular chemistry solvent and reagent that is used as an aroma compound, a stain remover, a superglue remover, a paint stripper, and a solvent in some wet aluminum electrolytic capacitors. View abstract. 2155404, is covered by three harmonisations: 005011004; 005011011 and 005011029), CLH information cannot be displayed in the InfoCard as the difference between the CLH classifications requires manual interpretation or verification. semiconductors. If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. Home My Account Saved Ads Help Contact Post A Free Ad Post In All Cities Post A Banner Ad. [7], -Butyrolactone is produced industrially by dehydrogenation of 1,4-butanediol at a temperature of 180300C and atmospheric pressure in the presence of a copper catalyst. This differs significantly from GHB, which is described as having a decidedly "salty" taste. Some of these muscle relaxants include carisoprodol (Soma), pipecuronium (Arduan), orphenadrine (Banflex, Disipal), cyclobenzaprine, gallamine (Flaxedil), atracurium (Tracrium), pancuronium (Pavulon), succinylcholine (Anectine), and others. Your email address will not be published. nh cung cp tuyt vi. Biol Psychiatry 1983;18:1023-32. Mamelak M. Gammahydroxybutyrate: an endogenous regulator of energy metabolism (abstract). GBL is unsafe. Prolonging life. Taking haloperidol (Haldol) along with GBL might cause serious side effects. adhesives and sealants, Influence of gamma-butyrolactone on behavior due to dopaminergic drugs (abstract). PDF Gamma-Butyrolactone (Street Names: GBL, Blue Nitro, Blue Nitro Vitality The resulting reverts to the monomer by thermal cracking. Thai D, Dyer JE, Benowitz NL, Haller CA. GBL might cause sleepiness and drowsiness. Haloperidol (Haldol) can also affect the brain. Mason P, Kerns II W. Gamma Hydroxybutyric Acid (GHB) Intoxication. Quality is good,I could easily peak serum levels.. Firstly, GBL is a lactone. Russia: GBL has been classified as a psychotropic substance since 22 February 2012. Our customer service answers all emails. Gamma-Butyrolactone. [27][28], There have been news reports of several deaths associated with GBL, usually in combination with alcohol or other depressants. Vitamin D Deficiency: How Much Vitamin D Is Enough? outdoor use as processing aid, gamma-Butyrolactone | C4H6O2 | CID 7302 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities . Release to the environment of this substance can occur from industrial use: June 15, 1999. Gamma-Butyrolactone Chemical compound. - Facebook The 2021 Regulations placed two controlled drugs, Gamma-Butyrolactone (GBL) and 1,4-Butanediol (1,4-BD), which have legitimate uses in industry, under stricter control, meaning that industrial users would require a controlled drugs licence. inks and toners. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and You have rejected additional cookies. The Prior Informed Consent Regulation administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries. Release to the environment of this substance can occur from industrial use: Formula Weight: 86. We are going to order again, Received my order, how will you package another 100L and send? This substance is used in the following areas: For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. a-Hydroxy-g-butyrolactone technical grade 19444-84-9 - Sigma-Aldrich GBL (gamma-butyrolactone) is a pro-drug of GH B, which means that it converts to GHB within the body. Near-fatal persistent anion- and osmolal-gap acidosis due to massive gamma-butyrolactone/ethanol intoxication. GBL is changed by the body to another chemical that can affect the brain. Naloxone overcomes the dopaminergic, EEG, and behavioral effects of gamma-hydroxybutyrate (abstract). Buy GAMMA-BUTYROLACTONE GBL Online, We also offer a variety of shipping services to deliver products to our clients in a variety of marketplaces and locations throughout the world. Home My Account Saved Ads Help Contact. This substance has been found in the following regulatory activities (directly, or inheriting the regulatory context of a parent substance): Welcome to the ECHA website. Gamma butyrolactone (GBL) is UNSAFE. Gamma-hydroxybutyrate: an overview of the pros and cons for it being a neurotransmitter and/or a useful therapeutic agent (abstract). The effects can be made worse by alcohol or narcotics such as morphine, heroin, and others. Maitre M. The gamma-hydroxybutyrate signaling system in brain: organization and functional implications (abstract). All rights reserved. The responsible Minister in Northern Ireland has made equivalent legislation in Northern Ireland to mirror this change. The 2021 Regulations were due to come into force on 15 June 2022. Its difficult to store because it requires a glass bottle or a certain sort of plastic bottle. Taking saquinavir with GBL might decrease how fast the body gets rid of GBL. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. GBL can be found in cheese flavorings but typically results in a content of 0.0002% GBL in the final foodstuff. Improving athletic performance. The intention was to prevent the open supply of these substances as bogus industrial products. To help us improve GOV.UK, wed like to know more about your visit today. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas. Fabio Giannessi, Maria Ornella Tinti, Francesco De Angelis, "Process for producing (R)-3-hydroxy-4-butyrolactone useful for preparing (R)-carnitine." Taking GBL along with alcohol can lead to serious side effects. . Use our structured and evidence-based datasets to unlock new insights and accelerate drug research. Hillory J. Farias and Samantha Reid date-rape drug prohibition act of 2000. [26] When combined with alcohol the increased sedation and risk of vomiting results in a high risk of fatality. : If the substance is covered by more than one CLH entry (e.g. : 19444-84-9; Synonyms: 4,5-Dihydro-3-hydroxy-2(3H)-furanone; Linear Formula: C4H6O3; Empirical Formula: C4H6O3; find related products, papers, technical documents, MSDS & more at Sigma-Aldrich. Cash CD. coating products, Neth J Med 2015;73(3):133-5. Build, train, & validate predictive machine-learning models with structured datasets. Feigenbaum JJ, Howard SG. View abstract. This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). It is a versatile cyclic ester that has a wide range of applications. Gamma-hydroxybutyrate intoxication and overdose. Equally important these compounds then may go on to form a polymer. This publication is available at https://www.gov.uk/government/publications/circular-0042022-gamma-butyrolactone-gbl-and-14-butanediol-14-bd-revocation-of-rescheduling/circular-0042022-gamma-butyrolactone-gbl-and-14-butanediol-14-bd-revocation-of-rescheduling. Amphetamines are drugs that can speed up the nervous system. Gamma Knife is a type of stereotactic radiosurgery. Required fields are marked *. Important message for health professionals: Report serious adverse events associated with dietary supplements containing GBL, GHB or BD. The Advisory Council on the Misuse of Drugs recommended that GBL and 1,4-BD should be placed in Schedule 1 to the 2001 Regulations and further recommended the removal of the exemption under regulation 4B of the 2001 Regulations, meaning that legitimate industrial users would require a controlled drugs licence [footnote 2]. Gamma Butyrolactone (Gbl) - eMedicineHealth Pentobarbital for severe gamma-butyrolactone withdrawal. Eur Addict Res 2011;17(4):169-71. Melting point 43.53 C (46.35 F; 229.62 K) Neurosci Biobehav Rev 1989;13:187-98. [Tianqi Niu, Jing Lu, Rahim Munir, Jianbo Li, Dounya Barrit, Xu Zhang, Hanlin Hu, Zhou Yang, Aram Amassian, Kui Zhao, and Shengzhong (Frank) Liu: "Stable High-Performance Perovskite Solar Cells via Grain Boundary Passivation", Advanced Materials, 2018, 1706576. GBL might cause sleepiness and drowsiness. Release to the environment of this substance can occur from industrial use: Injecting drug users continue to constitute 30 percent of these cases. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). in articles, Taking GBL along with some medications for pain might cause severe side effects. Buy GBL Gamma Butyrolactone Online J Addict Med 2011;5(4):302-3. The clinical toxicology of ?-hydroxybutyrate, ?-butyrolactone and 1,4-butanediol. GBL has a distinctive taste and odour, described as being comparable to stale water, synthetic melon aroma or burnt plastic. methyl-2-pyrrolidone. Hazards Substances which have been registered and can be placed on the EEA market by those companies with a valid registration. Gen Pharmacol 1992;23:1027-34. Neurosci Biobehav Rev 1994;18:291-304. Some medications for pain can cause sleepiness and drowsiness. Simultaneous stimulation of slow-wave sleep and growth hormone secretion by gamma-hydroxybutyrate in normal young Men (abstract). Long-term use may lead to withdrawal symptoms including insomnia, tremor, and anxiety. View abstract. GBL can affect the brain. See additional information. Eiden C, Capdevielle D, Deddouche C, et al. Product name: Gamma-Butyrolactone. This substance is used in the following products:
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