dr rhonda patrick joe rogan

Access exclusive muscle-building workouts and weight loss diets with our. ", Rogan has since walked back his controversial statements, asserting that he is "not a respected source of information," and saying: "I'm not a doctor. Your access to this site was blocked by Wordfence, a security provider, who protects sites from malicious activity. NDgxNWQxNTIwMDE3MTVlYjU4MDY4OTMwZTg2MDk3ZjRjNjFiMDIyNzVjNWU1 The Private Medical team is joined by Dr. Josh Woolley to discuss the latest research on how psilocybin and related compounds impact the FREE when you join over 50,000 subscribers to the Podcast Notes newsletter. All notes are intended to reflect the podcast and have not beenindependentlyverified. Patrick: I used to never get sick. MWE0M2IyODlhMmZmNTBkMTkzOGQ5YmFlYzVjZGJhMDNjNGM2ZjdiNjBiODkw . She has done extensive research on aging . OGNhMGJlMmYwNzkyNDg0Yjc3NmE1YzU1ZmE3OGQwMDJhODIxZGNkNDdmZDlh Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Logocentrifugal Podcast With Chance Lunceford, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Jolly Swagman Podcast with Joseph Walker, The Underworld Podcast with Danny Gold and Sean Williams, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Sauna: if you have access use the sauna regularly to improve cardiovascular health and immune functions take a hot bath if you dont have access, Theres a big difference between oral vitamin C and Intravenous vitamin C, You can take vitamin C orally but will need a big dose and it still wont have the same effect; IV once per week if you can, Sleep plays a crucial role in immunity, homeostasis, and regulation of body functions, People are actively working on monoclonal antibodies, Improved therapeutic treatments coming, including more repurposing of drugs that will make things less scary, As you get older your immune system declines, There are lifestyle components of immune system you can be proactive about: exercise, sleep, supplements, nutrition, gut-microbiome health, Besides age, the major regulator of immune function seems to be previous virus exposure, not genetics, At any given point you have antibodies against 10 different viruses but youre not always getting sick, 50-80% of US population has had CMV and most people dont ever know they have had it and show no symptoms, CMV impacts immune function differently depending on when you get it, When youre young, it enhances immune response but for older people its deleterious, Interesting tie-in to COVID-19 because we know older people are more prone to severity, Its likely that theres some cross-immunity happening since SARS-COV-2 viruses is part of beta coronaviruses along with SARS-CoV-1 and MRSA, 15-30% of common colds come from coronaviruses so theres a good hypothesis that potentially one or two of common cold virus antibodies could interact with SARS-CoV-2 and neutralize it, Antibody binds to virus and instead of neutralizing it, changes the configuration so the virus can get into the cell better, This activates the immune system and causes pathology, This results in a higher viral load without antibodies to neutralize, Weve seen it happen with coronaviruses, including SARS-CoV-1 and MRSA, The spike region is where antibodies bind and is also the region the virus uses to get into the cell, Currently seeing two major strain mutations in the spike regions one mutation more prominent in Asia, one mutation more predominant in Europe and North America, Brings to light an interesting genetic link to mutations, Theres a theory that the mutation is causing peoples immune system to become more active and lead to severe COVID-19, Monoclonal antibodies: identify specific antibody that binds to spike protein and manufacture them, Problem is this will offer short lived protection since you are not making your own antibodies as you would with a vaccine, Continuous exploration into repurposing drugs and combination drug treatments, Anecdotally, the majority of people on ventilators die partly because ventilators cause more damage to the lungs and can induce more damage, But its hard to say which came first did the ventilator do the damage or was the damage so severe that the patient needed a ventilator, People with Type O blood seem to be less susceptible to contracting COVID-19, People with Type O blood create Type A antibodies which bind to spike region and neutralize antibody so it cant enter the cell, We saw this in SARS-CoV-1 so maybe same for SARS-CoV-2, Another (unproven) theory: Type O blood people have lower levels of blood factor involved in clotting, Hearing more stories that some prisoners are trying to contract SARS-CoV-2 to get out of jail by spitting in a cup and passing to others, First off, its important to distinguish between asymptomatic and pre-symptomatic, Some people do not have symptoms at the time of testing but develop symptoms later so are actually pre-symptomatic, Its possible that viruses have already gone around that environment so antibodies from those viruses are helping in immunity from SARS-CoV-2, Rhonda was also searching to literature to see whether inmates are vaccinated prior to entering but couldnt find that information, Poor sleep has a huge impact on glucose and spikes and also plays a role in maintaining optimal immune functions, Rhonda takes melatonin to help her sleep, 10 mg/day, Regulating circadian rhythm is crucial for sleep, Rhonda makes sure to have bright light exposure in the morning (e.g., opening curtains, walking outside), and changes the lighting in the house in the evening to red lights, 70% of US population has insufficient Vitamin D levels; 28% are deficient, Body can generate naturally when exposed to sun daily, Obese people in US are also more likely to be vitamin D deficient, Genetic polymorphisms: people that have variations in genes that cause them to have less vitamin D, These people are more likely to die from respiratory infection, African Americans in the US are 28x more deficient in vitamin D than Caucasians, A recent study that looked at COVID-19 patients observed an inverse relationship between vitamin D levels and COVID-19 symptoms: the lower the vitamin D levels, the higher the severity of COVID-19, In Indonesia almost all patients that died from COVID-19 were vitamin D deficient, Melanin blocks ability to produce Vitamin D, In the US and Europe, African Americans and black people are more likely to die from COVID-19, Even when adjusting for SES and lifestyle factors, this was still true so something else must be happening, Tolerable upper intake is 4000 IUs per day but its best to get vitamin D blood test to measure levels, There are clinical studies exploring the role of vitamin D but not many in the US, Rhonda wants to see nurses and first responders take vitamin D to see the role in prevention but those studies are not being done, Joe uses the sauna 7 days/week, 180-degrees for 25 min, Rhonda uses the sauna 5 days/week, 180-degrees for 25 min, Heart rate variability improves, blood pressure goes down, cardiovascular health improves, all-cause mortality decreases, Sauna use also improves immune system and makes you more resilient against infection, Brain-derived neurotropic factors (BDNF) increases with exercise and heat stress (sauna), The positive benefits of physical activity on the cardiovascular system were enhanced when sauna was added, Sauna use increases heat shock proteins which prevent muscle atrophy, neurodegenerative genes, and have anti-depressant effects, People who sat in 160-degree sauna for 30 minutes had a 60% increase in heat shock protein compared to baseline, Large Harvard study being done to assess whether hot yoga increases heat shock protein, Heat shock protein have antiviral activity against influenza A, Regular sauna is heating ambient air which in turn raises core body temperature, Infrared saunas are directly heating body without heating the ambient air for example, in a heating tent or blanket, We know more about the effects of dry sauna, For people who dont have access to sauna, a hot bath is a good modality for heat shock protein, Studies being done to assess whether sauna can have anti-depressant effect on depressed patients, Saunas could also provide an avenue for giving sedentary and disabled people the benefits of physical activity without exercising, Ice baths and cold showers can be comparable to cryotherapy but you have to stay in the cold water longer, Cold shock protein hasnt really been measured in humans, instead whats measured is norepinephrine which has been shown to increase, Cold shock protein and hot shock protein have been shown to improve mood as well, The pharmacokinetics of vitamin C are very different in oral vs IV consumption, Oral vitamin C is good for immune function, etc. Because my father-in-law has apnea. List of JRE Rhonda Patrick Episodes : r/JoeRogan - Reddit She has dedicated her research career to finding proactive and preventive solutions to aging and longevity. You know like when youre working out hard sometimes you require more sleep? It calculates heart rate, body movement, and temperature. Its amazing. MzI2OGQ4YTBiODIyZWI1NDE1OGJkZjhhZDE3OWI5MmJhZThjN2QzMjQ4MzRh Joe Rogan and Rhonda Patrick cover a wide range of topics from pros and cons of ketosis, sauna use, the value of omega-3s, COVID, and much more. But duration is pretty accurate. NjkxYjdiZjVhNDUzM2I2Yzk1NDQ3ZDk0Nzg0MDM3ZmIwZTM4Zjc5ZDUxMDA3 There is an issue between Cloudflare's cache and your origin web server. Click to reveal ZTVlZjA3ODkyNTQ0YTQxZTExMmE2ZWVmMmNiOWFmYzMyZDA3YWM2ZTAxYWQx The Joe Rogan Experience: Dr. Rhonda Patrick Podcast Notes Its happened more than once. Dr. Rhonda Patrick has been making waves in the field of healthy aging. Preview of Spotify. We may earn commission from links on this page, but we only recommend products we back. Rogan: She loves it. Dr. Rhonda Patrick Goes In Depth on the Benefits of Vitamin D When the American Heart Association recently made a statement saying saturated fat led to heart disease, they didnt take this into account, When eaten in large quantities, the protein increases the production of the growth factor IGF-1, which can allow damaged cells to not die (basically allowing precancerous cells to form a tumor), If youre eating a good diet, and not causing as much damage in the first place, then having that much IGF-1 isnt as big of deal due to lack of damaged cells, Carcinogens are in charred meat (from the heterocyclinc amines HCAs that are formed), Our bodies have genes that can inactivate/detoxify these HCAs (through detoxification enzymes), people can do this to varying degrees, The Ames Test, created by Rhondas mentor, All animals/meat differ in their amino acid makeup and micronutrient concentrations, so its good to eat a diverse array of animal protein, Has 20,000x times the effect of ascorbic acid, so its a really powerful antioxidant, This makes a case for microbiome transplants, like fecal transplants, There are correlations between gut microbiome and chilldren with Autism and Asbergers, Parkinsons Disease, and Multiple Sclerosis, Some of the short chain fatty acids that certain species of bacteria in the microbiome make increase the production of natural killer T cells, In studies in which animals were injected with human tumors, and the animals took a large dose of probiotics which can make those short chain fatty acids, t, Non-nutritive sweetener (not like sucralose, aspertame (found in Diet Coke), and sacrine which can all mess up the microbiome it changes the composition so the bacteria that are really good at harvesting glucose increase in number, causing people to become obese), Some studies have shown it improves insulin sensitivity, We havent really seen negative health consequences, but Rhonda didnt consume any during pregnancy, So, you cant eat a shitty diet, then take probiotics, Xantham gum isnt that bad, but other emulsifiers in hot sauces for example, can disrupt the gut microbiome, Higher rates of Type I diabetes in offspring, lower cognition scores, Its hard to do causal studies showing this (in which you would feed someone high inflammatory foods during pregnancy, as its unethical), so all the scientific data is from animal studies, or looking specifically at obese mothers who are thought to have eaten badly during pregnancy, Paternal age (the fathers age) has been linked to autism, also smoking, Maternal Age has been linked to Down Syndrome, The obesity changes genes that regulate pancreatic beta cell insulin production in their sperm DNA, which is passed on to the offspring, Rhonda is doing a lot of high intensity spin training, She also did a lot of walking during her pregnancy, She wants to incorporate more strength training , When running, youre supposed to land on the ball of your foot, Nike started putting large heels in the back of sneakers, so people started running on their heels, He says his feet have become stronger, and his arches have improved, The next podcast with Rhonda and Joe will be recorded in the sauna.

Steven Spielberg Grandchildren, Sensormatic Troubleshooting, Viva St Uk, Why Are Some Butterfingers Hard, Articles D