The site youre being redirected to is a branded pharmaceutical website. The NCCN Prostate Cancer Panel uses the term castration-naive even when patients have had neoadjuvant, concurrent, or adjuvant ADT as part of radiation therapy provided they have recovered testicular function. National Comprehensive Cancer Network, Inc. 2019. Janssen Research & Development, LLC is one of the Janssen Pharmaceutical Companies of Johnson & Johnson. RELATED: A Major New Effort Announced to Vaccinate Young Boys Against HPV and Cancers Linked to Sex. "That's a team that's right there. If youre experiencing symptoms such as changes in bowel movements you shouldnt be embarrassed to talk to a doctor about it.. And with the support of our friends and their generous gifts, our researchers will be able to continue their dedicated work to improve outcomes for cancer patients all over the world.. *9 The NCCN Guidelines also include apalutamide (ERLEADA) with androgen deprivation** as a Category 1 Preferred treatment option for patients with metastatic (M1) castration-naive prostate cancer.*[ix] The American Urological Association (AUA) Guidelines for Castration-Resistant Prostate Cancer (CRPC) recommend clinicians offer apalutamide (ERLEADA) with continued androgen deprivation therapy (ADT) as one of the treatment options for patients with nmCRPC at high risk for developing metastatic disease. January 19, 2021. I see patients who will say, look, why would you radiate itwhen its still there? In September 2019, ERLEADA received FDA approval for the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC) based on results In October 2022, Johnson signed a long-term contract extension with Warner Bros. Through active surveillance, doctors monitor whether the tumor is shrinking or growing. [citation needed] Johnson played first base on the Bulldogs baseball team his freshman year. This press release contains "forward-looking statements" as defined in the Private Securities Litigation Reform Act of 1995 regarding product development and the potential benefits and treatment impact of ERLEADA (apalutamide). The key global companies of Prostate Cancer include Astellas, Inc., AstraZeneca plc, Johnson and Johnson, Sanofi S.A, Bristol Myers Squibb (BMS) and Bayer Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3. 2015;9(3-4):90-96. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455631/. About Non-Metastatic Castration-Resistant Prostate CancerNon-metastatic castration-resistant prostate cancer (nmCRPC) refers to a disease stage in which the cancer no longer responds to treatments that lower testosterone but has not yet been discovered in other parts of the body using a total body bone scan and/or CT/MRI scan. Consider discontinuation of ERLEADA for Grade 3 and 4 events. I also have a personal perspective: My father was diagnosed with prostate cancer many years ago, when I was in college. MILWAUKEE (CBS 58) -- Friday night, NBA broadcaster Ernie Johnson, Jr. was honored at Fiserv Forum with the Vince Lombardi Cancer Foundation's Award of Excellence. at nine on upfront tnt. Hudson was diagnosed with prostate cancer The foundation raises money for cancer research and honors a significant figure from the sports world every year. The interview concept has inspired similar events in Las Vegas, Nevada; Atlanta, Georgia; Washington, D.C.; and Houston, San Antonio and Corpus Christi, Texas, raising more than $46 million for cancer research and patient programs at MD Anderson. Actor: Hustle. "There are a lot of changes in the city, but the neighborhood looked exactly the same," he said. Accessed May 2020. [viii] American Cancer Society. Johnson returned to Inside the NBA on October 31, 2006, while continuing his chemotherapy treatments. In 2003, Johnson was diagnosed with non-Hodgkin lymphoma, a type of cancer found in the lymphatic system. It appears that when androgen production is inhibited, DNA repair in cancerous cells slows down. sign up for the wires and see archived wires, Browse experts available to comment on breaking news, Request an expert contact, get responses directly to your inbox, Find an expert by topic in a comprehensive database. * Referenced from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Prostate Cancer V.1.2020. He dealt with his diagnosis privately until he announced his cancer in 2006. Why is there such an urgent need for treatments for this type of prostate cancer? Sports fans, cancer survivors, fathers and sons, adoptive parents, those whose lives have been touched by a person with special needs, anyone who loves stories about handling life's surprises with grace--Unscripted is for all of these. In 2003, Johnson was diagnosed with non-Hodgkin lymphoma, a type of cancer found in the lymphatic system. It is unknown whether anti-epileptic medications will prevent seizures with ERLEADA. Were not advocating this combination approach for all patients with prostate cancer at this time but rather taking a personalized approach based on presence of mutation. We are evaluating combination approaches that interrupt the androgen-making process as well as impact the tumors ability to repair DNA to make treatments even more effective. Roche nixes Tecentriq trial in early breast cancer, but it's 'still in the game' in key lung cancer use: exec. The company is in the midst of clinical trials to potentially bring a new form of prostate cancer treatment to patients with this common gene mutation and a panel of other gene mutations, such as FANCA, PALB2, CHEK2, BRIP1, HDAC2 and ATM, which are actively being evaluated in clinical trials. Were the Pharmaceutical Companies of Johnson & Johnson, working tirelessly to make that future a reality for patients everywhere by fighting sickness with science, improving access with ingenuity, and healing hopelessness with heart. None of the Janssen Pharmaceutical Companies nor Johnson & Johnson undertakes to update any forward-looking statement as a result of new information or future events or development [i] Small, E. et al. broadcaster and milwaukee native ernie johnson, honored in his hometown tonight. National Comprehensive Cancer Network, Inc. 2020. Give Light and the People Will Find Their Own Way. ERLEADA is currently approved in over 65 countries, and labels are being updated globally to reflect data from the SPARTAN final analysis. Where was Ernie Johnson born? Please see our Privacy Policy. Don't have an account? Risk Factors, and in the companys most recently filed Quarterly Report on Form 10-Q, and the companys subsequent filings with the Securities and Exchange Commission. Falls In a randomized study (SPARTAN), falls occurred in 16% of patients treated with ERLEADA compared to 9% of patients treated with placebo. The Internet launched publicly 30 years ago. The Prostate Cancer Treatment market has witnessed growth from USD million to USD million from 2017 to 2023. Now the actor, 74, wholl appear in Ghostbusters: Afterlife in 2021, is raising awareness ofthree cancer-causing viruses through the Think About The Link initiative. These gene variants dramatically increase the risk of developing prostate cancer, especially life-threatening prostate cancer. A Prostate Cancer Early Detection Project has been launched to improve prostate cancer diagnosis, care and management for men aged 40 years and above in the Ghana Armed Forces. Event chairs for the 2021 Living Legend event, comprised of past Living Legend Chairs from Houston and San Antonio, include: 1-713-792-0655 Ernie Johnson Jr.'s cancer diagnosis NBA TNT Analyst Ernie Johnson talks outside the Chase Center before the LA Clippers game against the Golden State Warriors on October 24, 2019, in San Francisco, California. Falls were not associated with loss of consciousness or seizure. Read more here. Individual tickets are available beginning at $150 at www.mdanderson.org/winterlegend2021. Johnson is currently the television voice and a studio host for Major League Baseball on TBS, hosts Inside the NBA for TNT, and NBA TV and contributes to the joint coverage of the NCAA Division I men's basketball tournament for Turner and CBS Sports. It can be benign prostatic hyperplasia, prostate cancer, or prostatitis, which itself is a mystery within a mystery to which Johnson devotes a chapter. Bringing awareness to the HPV vaccine and its ability to prevent at least six types of cancer is truly stopping cancer before it starts, Hudson says. They have four children. Register, Ghostbuster, Ernie Hudson, Survived Cancer Twice Now Hes Determined To Help Others Prevent It, Weeks Before Wedding, 32-Year-Old Mom Diagnosed With Stage 4 Bowel Cancer: The Reason She Was at High Risk, Docs Dimiss 27-Year-Old's Bowel Cancer Symptoms for Years as Stress, Other Health Issues: Ready to 'Start Living My Life' Again After Aggressive Treatments, Biloxi Woman Shocked Home Stool Test Was Negative Before Colon Cancer Diagnosis, Marcia Cross' Kids Were Angry When She Got Cancer How That 'Trauma' Turned Into Loving Support, Transthyretin Amyloid Cardiomyopathy (ATTR-CM), some doctors recommend active surveillance, mostly involve people being unaware or too embarrassed. This site is governed solely by applicable U.S. laws and governmental regulations. For early-stage prostate cancer, some doctors recommend active surveillance, a watch-and-wait approach for men who have a small number of cancer cells found in the biopsy, a lowPSA, and low-grade cancer. For Johnson's father, the former pitcher and broadcaster, see, Learn how and when to remove this template message, NCAA Division I men's basketball tournament, Outstanding Sports Personality, Studio Host, NCAA men's basketball tournament on CBS/TBS/TNT/TruTV, "Thanks Turner family it's the only place I've ever wanted to work29 years and counting", "ERNIE JOHNSON, JR. - HARTMAN AWARD RECIPIENT", "TNT Announces 'Inside the NBA' Crew's Future Amid Charles Barkley Contract", "Ernie Johnson of TNT gives Sports Emmy Award to Stuart Scott's daughters", "Michael Johnson, son of Turner Sports broadcaster Ernie Johnson, dead at 33", "TNT Host Ernie Johnson "Trust God Period", "Announcer Ernie Johnson will skip MLB playoffs due to blood clots", Brown, Kirkpatrick, MacMullen, and Scott voted into NSMA HOF NSMA, "Ernie Johnson Jr. inducted as 2019 IWU World Changer", Roy Halladay's postseason no-hitter (2010), NCAA Men's Division I Basketball Championship, Sports Emmy Award for Outstanding Sports Personality, Studio Host, https://en.wikipedia.org/w/index.php?title=Ernie_Johnson_Jr.&oldid=1149447779, College basketball announcers in the United States, National Basketball Association broadcasters, BLP articles lacking sources from October 2021, Short description is different from Wikidata, Articles with unsourced statements from October 2021, Articles lacking reliable references from October 2021, BLP articles lacking sources from October 2015, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 12 April 2023, at 09:06. Risks and uncertainties include, but are not limited to: challenges and uncertainties inherent in product research and development, including the uncertainty of clinical success and of obtaining regulatory approvals; uncertainty of commercial success; manufacturing difficulties and delays; competition, including technological advances, new products and patents attained by competitors; challenges to patents; product efficacy or safety concerns resulting in product recalls or regulatory action; changes in behavior and spending patterns of purchasers of health care products and services; changes to applicable laws and regulations, including global health care reforms; and trends toward health care cost containment. Contract & Freelance Partner Opportunities, Do Not Sell or Share My Personal Information, Limit the Use of My Sensitive Personal Information, https://meetinglibrary.asco.org/record/187437/abstract, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455631/, https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2020/cancer-facts-and-figures-2020.pdf, http://www.auanet.org/guidelines/castration-resistant-prostate-cancer-(2013-amended-2018), Hematology In TITAN study, white blood cell decreased ERLEADA, Chemistry In TITAN study, hypertriglyceridemia ERLEADA. But more than 20 years ago, He credited faith, friends and family for helping him during his battles, and hes hoping to share some of that strength with others also battling cancer. A Prostate Cancer Early Detection Project has been launched to improve prostate cancer diagnosis, care and management for men aged 40 years and above in the Risk factors include a family history of colon cancer, smoking, and obesity. Find information and resources for current and returning patients. Hypothyroidism In two randomized studies, hypothyroidism, was reported for 8% of patients treated with ERLEADA and 2% of patients treated with placebo based on assessments of thyroid-stimulating hormone (TSH) every 4 months. Scher HI, et al. The virtual event airing Feb. 4 at noon and 6 p.m. CST will weave together the stories of three extraordinary people who have been touched by cancer: Roberts, Johnson and the late sports reporter Craig Sager. There were no Grade 3 or 4 adverse reactions. Related:When Is Active Surveillance Not Enough? Apr 26, 2023 09:17am. A Prostate Cancer Early Detection Project has been launched to improve prostate cancer diagnosis, care and management for men aged 40 years and above in the Ghana Armed Forces. Johnson knows the importance of this mission well, having survived two cancer diagnoses in his life. That's all I'm trying to do; what I've experienced with cancer and at least try to make it easier for the next person to get through it. I'm kind of shaking my fist at God, saying why me? How You should view the News section and the most recent SEC Filings in the Investor section in order to receive the most current information made available by Johnson & Johnson Services, Inc. Certain gene mutations can dramatically increase the risk of developing aggressive prostate cancer. Do Not Sell or Share My Personal InformationLimit the Use of My Sensitive Personal InformationCookie Settings. The message is, when you're in this club nobody wants to be in, you have the responsibility and the opportunity to help the next person through it.". Voting 111, with one abstention, the ODAC agreed that Lynparza Ernie Johnson was 5-9 (175 cm) tall. As part of its 10-year legacy in prostate cancer innovation, the Janssen Pharmaceutical Companies of Johnson & Johnson has made it its mission to help these patients. He credited faith, friends and family for helping him during his battles, and hes hoping to Born and raised in Milwaukee until age 8, Ernie Johnson will return to accept the Vince Lombardi Award of Excellence after battling non-Hodgkin lymphoma, and In 2006, Johnson won the award again, this time on his own, snapping Costas's six-year stranglehold on it, including the year the two shared the honor. Language links are at the top of the page across from the title. Ernie Johnson was born in Grand Rapids, Michigan. Then, in 2011, he was told he had rectal cancer. For all NBA-related shows, Johnson is joined by former NBA stars Kenny Smith, Charles Barkley, Shaquille O'Neal and, on occasion, Chris Webber, Grant Hill, or Reggie Miller. The reader is cautioned not to rely on these forward-looking statements. The touching eulogy he gave at his friends funeral reflected his understanding of the difficult toll that cancer treatment can take. With the CAGR of Percentage, this market is estimated to reach USD million in 2030. A further list and descriptions of these risks, uncertainties and other factors can be found in Johnson & Johnson's Annual Report on Form 10-K for the fiscal year ended December 29, 2019, including in the sections captioned Cautionary Note Regarding Forward-Looking Statements and Item 1A. https://meetinglibrary.asco.org/record/187437/abstract. Robin Roberts, an anchor of Good Morning America, will join Emmy Award-winning sportscaster Ernie Johnson Jr. for a virtual fireside chat with a special guest appearance by 11-time NBA All-Star Charles Barkley. WebErnie Hudson is best known for his role in the 1984 cult classic, Ghostbusters; however few fans know him as two-time cancer survivor. 2 Big Ideas to Help Lower the Risk of Maternal-Fetal Complications in BIPOC Women. Merck (MRK) and AstraZeneca (AZN) fell sharply Wednesday after the FDA issued its views ahead of an AdCom meeting on prostate cancer drug Lynparza. WebThis is the untold story, the one Ernie has lived after the lights are turned off and the cameras stop rolling. [iii] The SPARTAN study enrolled 1,207 patients who were randomized 2:1 to receive either ERLEADA orally at a dose of 240 mg once daily in combination with ADT (n=806) or placebo once daily in combination with ADT (n=401).3, Warnings and Precautions include ischemic cardiovascular events, fractures, falls, seizure and embryo-fetal toxicity.3 In the SPARTAN study, the most common adverse reactions (10 percent) were fatigue, hypertension, rash, diarrhea, nausea, weight decreased, arthralgia, falls, hot flush, decreased appetite, fracture and peripheral edema.3. However, there are people out there with certain oncological mutations that we may be able to target with treatment in the future. Never want to see this again? First of all, what are BRCA mutations, and how do they play a role in prostate cancer? Rash In two randomized studies, rash was most commonly described as macular or maculo-papular. Permanently discontinue ERLEADA in patients who develop a seizure during treatment. "My faith, my family, my friends. While Ernie and his wife were watching an episode of NBCs 20/20 about Romanian babies in orphanages, they realized that they had to adopt one of the Romanian babies. In a randomized study (TITAN) in patients with mCSPC, ischemic cardiovascular events occurred in 4% of patients treated with ERLEADA and 2% of patients treated with placebo. This changed in May 2007 when vitaminwater stepped in as a sponsor for the segment, replaced by Panasonic's Viera line of televisions for 2008. [ix] NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Prostate Cancer V.4.2019. In 2015, Johnson won his third Sports Emmy for Best Studio Host, and gave his award to the daughters of the late Stuart Scott, who died in January 2015. In 2020, Johnson moved back into a studio host for the network's pregame and postgame show while continuing his play-by-play role for TBS's coverage of Major League Baseball. Our newsletter vital information, hope, and healing, delivered weekly. A 2016 study published in the New England Journal of Medicine, for example, found that risk of metastatic prostate cancer was more common in patients with genetic mutations compared to noncarriers. The vast majority of humans in the U.S. will eventually get infected with human papillomavirus, says Dr. Allen S. Ho is a head and neck surgeon at Cedars-Sinai Medical Center. 2016;34:1402-1418. He dealt with his diagnosis privately until he Johnson says that he leaned on his Constance Costas is a writer for SurvivorNet. Getting tested for cancer saved my life. While giving his remarks, Johnson talked about the build-up to Election Day, and how he would lean on his Christian faith and pray for the transition of power and for the division in the country. J Clin Oncol. From 2007 to 2009, Johnson worked as the studio host alongside Cal Ripken Jr. for TBS's coverage of Major League Baseball. **Orchiectomy, LHRH agonist, or LHRH antagonist. Ischemic cardiovascular events, including events leading to death, occurred in patients receiving ERLEADA. He is a producer and actor, known for Hustle (2022), Space Jam: A New Legacy (2021) and Survivor's Remorse (2014). Use of this site constitutes your consent to application of such laws and regulations and to our Privacy Policy. More Ways Johnson & Johnson Is Working to Eliminate Cancer. Contact Us with any questions or search this site for more information. [x] American Urological Association. That's what gets you through times like this," Johnson says. His father, Ernie Johnson Sr. (19242011), was a Major League Baseball player who later became a television sports commentator. I tell [my patients] that you shouldnt die from fear,and you shouldnt die from embarrassment and thats really the only two reasonsthat people are dying from this disease today, Dr. Murrell said. Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group. Of the patients who had dose interruption, 59% experienced recurrence of rash upon reintroduction of ERLEADA. Our patients depend on blood and platelet donations. WebDue to his cancer, Johnson missed TNT's coverage of the British Open and PGA Championship, the last two golf major tournaments in 2006. 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He worked there as a news anchor until 1981, when he worked as a news reporter in Spartanburg, South Carolina, at WSPA-TV. From left: Robin Roberts, the late Craig Sager and Ernie Johnson Jr. Learn about our graduate medical education residency and fellowship opportunities. Today Show Host, Craig Melvins brother is a colon cancer survivor, and was diagnosed at stage 4: If you get screened, if you listen to your body, its the most treatable cancer.. The Johnsons have two biological children (Eric and Maggie) and four adopted children: a son named Michael, who was adopted from Romania, had Duchenne muscular dystrophy, and died in 2021;[9] a daughter named Carmen, who was adopted from Paraguay; and daughters Ashley and Allison, adopted domestically through foster care. By Hallie LevineOctober 11, 2021. Very rare May snow expected Monday with rain and wind. ERLEADA IMPORTANT SAFETY INFORMATION3WARNINGS AND PRECAUTIONS. It makes sense to assume that targeting both pathways in cells may lead to more cancer-cell deaths than targeting either pathway alone. Your use of the information on this site is subject to the terms of our Legal Notice. One way to do that for some patients with prostate cancer with a specific mutation is through drugs known as poly (ADP-ribose) polymerase, or PARP, inhibitors. J Clin Oncol. That's why Johnson & Johnson is researching a new way to fight the diseaseone that involves blocking cancer cells from repairing their own damaged DNA. WebFor more information about A Conversation With a Living Legend, contact Mary Prator at 713-563-4038 or MDPrator@mdanderson.org. Call us at 1-877-632 For example, a survey published earlier this year in the Journal of the Canadian Urological Association found that only a little over a third of oncologists recommended that their patients with newly diagnosed metastatic prostate cancer go for genetic testing. Pharmaceutical Companies of Johnson & Johnson, Reimagining the Way Healthcare Is Delivered, Meeting the Personal Care and Wellness Needs of Consumers Worldwide, Advancing New Healthcare Solutions Through Collaboration, Learn About the Company's Rich Heritage at Our Digital Museum. In September 2019, ERLEADA received FDA approval for the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC) based on results from the Phase 3 TITAN study, which achieved statistical significance in the dual primary endpoints of OS and radiographic progression-free survival (rPFS). MD Anderson will posthumously award Sager, his wife, Stacy, and the SagerStrong Foundation with the Making Cancer History Award, established in 2007 to recognize visionaries who are committed to MD Andersons mission to end cancer. Johnson says that he leaned on his faith, family, and friends to get through difficult times. Craig Sager was diagnosed with AML in 2014. Choose from 12 allied health programs at School of Health Professions. If future Accessed May 2020. Johnson and his wife Cheryl have four adopted children, including Michael who was born with a progressive form of muscular dystrophy and lives on a ventilator in his parents home. Ernie Johnson Jr. is an Emmy Award-winning sportscaster for Turner Sports, lead television voice for Major League Baseball and host of NBA coverage on Turner Network Television (TNT). Photo: George Napolitano/FilmMagic. The NBA awarded Roberts the Sager Strong Award in 2019 after her story inspired hundreds of potential bone marrow donors to register and heightened awareness about a rare type of cancer. Most People Will Get This Virus. They are also sometimes called tumor suppressor genes, and when they have certain variants or mutations, cancer can develop. in patients (pts) with nonmetastatic castration-resistant prostate cancer (nmCRPC). But Fewer People Know It Can Cause Cancer: Concerning New Evidence About HPV. MD Andersons A Conversation with a Living Legend series began in North Texas. Friday, the FDAs Oncologic Drugs Advisory Committee (ODAC) threw its support behind Mercks and AstraZenecas PARP inhibitor Lynparza (olaparaib), but only in a subset of metastatic castration-resistant prostate cancer (mCRPC) patients carrying a particular tumor mutation. Friday, the FDAs Oncologic Drugs Advisory Committee (ODAC) threw its support behind Mercks and AstraZenecas PARP inhibitor Lynparza (olaparaib), but only in No initial dose adjustment is necessary; however, reduce the ERLEADA dose based on tolerability [see Dosage and Administration (2.2)]. [vii] Saad F, et al. "My Job Is to Educate About the Need for New Treatments for Rare Diseases". Embryo-Fetal Toxicity The safety and efficacy of ERLEADA have not been established in females. WebErnie Johnson. "I was stunned, and I think that hit me the first time that I went up to Whistling Straits and then I made some time on the way back to go through the old neighborhood. He became the station's weekend sports anchor and reporter in 1983. Our hope is that by having targeted treatments available early in the disease process for prostate cancer patients with these mutations, we can identify these patients at the time of their diagnosis and potentially significantly improve their outcomes. So Johnson & Johnson Innovation challenged researchers to propose potential solutions that aim to address this troubling healthcare disparity. My sister had just been diagnosed with multiple myeloma, and Janssen was making fantastic progress in the field. In April 2017, he released his memoir, Unscripted: The Unpredictable Moments That Make Life Extraordinary.[1]. According to a phase 2 study conducted by the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy, the monoclonal antibody enoblituzumab is deemed safe for use in men with aggressive prostate cancer and has the potential to induce clinical activity against cancer throughout the body. About ERLEADAERLEADA (apalutamide) is an androgen receptor (AR) inhibitor indicated for the treatment of patients with nmCRPC and for the treatment of patients with mCSPC.3 ERLEADA received FDA approval for nmCRPC on February 14, 2018, and was approved for mCSPC on September 17, 2019.3 ERLEADA is taken orally, once daily, with or without food.3 The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines ) for Prostate Cancer include apalutamide (ERLEADA) with continued androgen deprivation therapy** as a Category 1 Preferred treatment option for patients with non-metastatic (M0) castration-resistant prostate cancer and a PSADT 10 months.
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ernie johnson prostate cancer